Genetic Modifiers of Retinal Degeneration in therd3Mouse
نویسندگان
چکیده
منابع مشابه
Genetic modifiers of retinal degeneration in the rd3 mouse.
PURPOSE In previous studies of light-induced (LRD) and age-related (ageRD) retinal degeneration (RD) between the BALB/cByJ (BALB) and B6(Cg)-Tyr(c-2J)/J (B6a) albino mouse strains, RD-modifying quantitative trait loci (QTLs) were identified. After breeding BALB- and B6a-rd3/rd3 congenic strains and finding significant differences in RD, an F1 intercross to determine rd3 QTLs that influence this...
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*Correspondence: Stephen H. Tsang, M.D., Ph.D., Columbia College of Physicians & Surgeons, Harkness Eye Institute Research Annex 513, 160 Fort Washington Avenue, New York, NY 10032. Tel: (212)-342-1189, Fax: (212)-305-4987, Email: [email protected]
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ژورنال
عنوان ژورنال: Investigative Opthalmology & Visual Science
سال: 2008
ISSN: 1552-5783
DOI: 10.1167/iovs.08-1715